Mefenamic acid + Paracetamol Pharmacology

Side Effects


Mechanism of action of mefenamic acid

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Nonsteroidal anti-inflammatory drugs including mefenamic acid may rarely increase the risk for a sometimes fatal heart attack or stroke. This effect does not apply to low-dose aspirin.

See Drug Interactions section. This effect can happen at any time while taking this drug but is more likely if you take it for a long time. The risk may be greater if you have heart disease or increased risk for heart disease for example, due to smokingfamily history of heart diseaseor conditions such as high blood pressure or diabetes.

Do not take this drug right before or after heart bypass surgery CABG. Also, this drug may rarely cause serious rarely fatal bleeding from the stomach or intestines. This bleeding can occur withoutwarning symptoms at any time during treatment. Stop taking this medication and seek immediate medical attention if you notice any of the following rare but very serious side effects: See also Precautions section. Talk with your doctor or pharmacist about the risks and benefits of treatment with this medication.

Who should not take Mefenamic Mechanism of action of mefenamic acid Mefenamic acid is used for the short-term treatment of mild to moderate pain from various conditions. It is also used to decrease pain and blood loss from menstrual periods. Read the Medication Guide provided by your pharmacist before you start using mefenamic acid and each time you get a refill, mechanism of action of mefenamic acid.

If you have any questions, consult your doctor or pharmacist. Take this medication by mouthusually 4 times a day with a full glass of water 8 ounces or milliliters or as directed by your doctor. Do not lie down for at least 10 minutes after taking this drug. If stomach upset occurs, take this medication with food or milk, mechanism of action of mefenamic acid. Do not take mefenamic acid with antacids unless directed by your doctor.

Certain antacids may change the amount of mefenamic acid absorbed by the body. Dosage is based on your medical condition and response to therapy. To reduce your risk of stomach bleeding and other side effects, take this medication at the lowest effective dose for the shortest possible time.

Do not increase your dose, take it more frequently, or take it for a longer time than prescribed. This medication usually should not be taken for more than 7 days at a time. If you are taking this drug on an "as needed" basis not on a regular scheduleremember that pain medications work best if they are used as the first signs of pain occur. If you wait until the symptoms have worsened, the medicine may not work as well. If you are using this medication for painful periods, take your first dose as soon as your period starts or pain begins.

Usually, you will only need to take it for the first 2 to 3 days of your period. What conditions does Mefenamic Acid treat?

Upset stomachnauseaheartburndizzinessdrowsiness, diarrheaand headache may occur. If any of these effects persist or worsen, notify your doctor or pharmacist promptly. Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects. This medication may raise your blood pressure. Check your blood pressure regularly and tell your doctor if the results are high.

Tell your doctor right away if any of these unlikely but serious side effects occur: Stop taking mefenamic acid and tell your doctor right away if any of these rare but very serious side effects occur: This drug may rarely cause serious, possibly fatal liver disease.

If you notice any of the following rare but very seriousside effects, stop taking mefenamic acid and consult your doctor or pharmacist right away: A very serious allergic reaction to this drug is rare. However, get medical help right away if you notice any symptoms of a serious allergic reactionincluding: This is not a complete list of possible side effects.

If you notice other effects not listed above, contact your doctor or pharmacist. Call your doctor for medical advice about side effects. In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at List Mefenamic Acid side effects by likelihood and severity.

Before taking mefenamic acidtell your doctor or pharmacist if you are allergic to it; or to aspirin or other NSAIDs e. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

This medication should not be used if you have certain medical conditions. Before using this medicine, consult your doctor or pharmacist if you have: Before using this medication, tell your doctor or pharmacist your medical history, especially of: Problems are more likely to occur if you are dehydrated, have heart failure or kidney disease, mechanism of action of mefenamic acid, are an older adult, or if you take certain medications see also Drug Interactions section.

Drink plenty actonel lawsuit netherlands holland fluids as directed by your doctor to prevent dehydration and tell your doctor right away if you have a change in the amount of urine. This drug may make you dizzy or drowsy. Alcohol or marijuana can make you more dizzy or drowsy.

Do not drive, use machinery, or do anything that needs alertness until you can do it safely. Talk to your doctor if you are using marijuana. This medicine may cause stomach bleeding, mechanism of action of mefenamic acid.

Daily use of alcohol and tobacco, especially when combined with this medicine, may increase your risk for stomach bleeding. Limit alcohol and stop smoking. Consult your doctor or pharmacist for more information. This medication may make you more sensitive to the sun. Limit your time in the mechanism of action of mefenamic acid. Avoid tanning booths and sunlamps. Use sunscreen and wear protective clothing when outdoors. Kidney function declines as you grow older.

This medication is removed by the kidneys, mechanism of action of mefenamic acid. Therefore, caution is advised when using this drug in the elderly because they may be more sensitive to its mechanism of action of mefenamic acid effects, especially stomach bleeding and kidney problems.

Before using this medication, women of childbearing age should talk with their doctor s about the benefits and risks such as miscarriagetrouble getting pregnant.

Tell your doctor if you are pregnant or if you plan to become pregnant. During pregnancymechanism of action of mefenamic acid, this medication should be used only when clearly needed. This drug passes into breast milk and may have undesirable effects on a nursing infant. Consult your doctor before breast -feeding. What should I know regarding pregnancy, nursing and administering Mefenamic Acid to children or the elderly?

Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not mechanism of action of mefenamic acid all possible drug interactions.

Some products that may interact with this drug include: This medication may increase the risk of bleeding when taken with other drugs that also may cause bleeding. These drugs are similar to mefenamic acid and may increase your risk of side effects if taken together. However, if your doctor has directed you to take low-dose aspirin to prevent heart attack or stroke usually at dosages of milligrams a dayyou should continue taking the aspirin unless your doctor instructs you otherwise.

Ask your doctor or pharmacist for more details. This medication may interfere with certain laboratory tests e. Make sure laboratory personnel and all your doctors know you use this drug. Does Mefenamic Acid interact with other medications?

If someone has overdosed and has serious symptoms such as passing out or trouble breathingcall Otherwise, call a poison control center right away. US residents can call their local poison control center at Canada residents can call a provincial poison control center. Symptoms of overdose may include: Consult your doctor for more details. If you are taking this drug on a regular schedule not "as needed" and you miss a dose, take it as soon as you remember.

If it is near the time of the next dose, skip themissed dose and resume your usual dosing schedule. Do not double the dose to catch up. Store at room temperature between degrees F degrees C away from light and moisture. Brief storage between degrees F degrees C is permitted. Do not store in the bathroom.


Mechanism of action of mefenamic acid